The science center is one of the original 1968 campus buildings designed by the world-renowned architect, Marcel Breuer. It connects University Hall and the Clairmont Center for Performing Arts and provides classrooms, laboratories, a computer lab, and faculty offices for mathematics and natural sciences in the School of Arts and Sciences and for the School of Health Sciences. It also houses the campus mailroom, print shop, and heating unit boiler.
In 2005, science hall became known as the Harold J. Miller Center in recognition of Dr. Harold J. and Carole Miller. Dr. Miller--"a leader developing leaders, a visionary shaping the future, a native son believing in North Dakota"--served as vice president and academic dean from 1968-1970, as fourth president 1970-1978, and as chairman of the board in a model known as dual leadership with the president from 1978-2005.