To meet the need for expanded facilities and an increasing nursing student enrollment, the Mary College Nursing Education Center was completed in 1976. It was the first connecting addition to the original 1968 campus buildings. It became the main reception area for the campus and provides switchboard service. The Casey Center houses School of Health Sciences classrooms and faculty offices, nursing assessment and modalities labs, a nursing simulation lab, and a study area. O'Keeffe Hall, an auditorium-type 101-seat classroom named in recognition of the gift of Adeline (Addie) O'Keeffe of Billings, Montana in memory of her husband J.J. (Jack) O'Keeffe is in the Casey Center.
In 1997 the Nursing Education Center was named the Casey Center for Nursing Education in recognition of Clem and Meredith Casey "whose enduring faith and generosity to the University of Mary assured its beginnings and continuation as a center of Christian learning." A far-sighted practitioner in long-range planning and Bismarck land developer, T. Clem Casey established a charitable trust to assure fulfillment of his strong commitment to Catholic education and the Bismarck community. The University of Mary (Mary College) and Bismarck parochial schools were the beneficiaries.